. Energy News .

World's first handmade cloned transgenic sheep born in China
by Staff Writers
Shenzhen, China (SPX) Apr 26, 2012

In 2009, donor cells were collected from a Chinese Merino sheep, and by genetic manipulation a transgenic cell line was established. After numerous attempts, the HMC system for sheep cloning was successfully established in October 2011. The transfer of the produced embryos has eventually led to the present achievement.

Chinese scientists from BGI, the world's largest genomics organization, together with the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences (CAS), and Shihezi University, Xinjiang province, made a significant breakthrough in animal cloning.

The world's first transgenic sheep produced with a simplified technique, handmade cloning, was successfully born at 12:16pm, March 26, 2012, in Xinjiang Uygur Autonomous Region, China. The project was also supported by the Animal Science Academy of Xinjiang.

"The transgenic sheep is named 'Peng Peng' (after the identical given names of the two cloners), his birth weight was 5.74 kg." said excitedly Dr. Yutao Du, Director of BGI Ark Biotechnology Co., LTD. (BAB), one of BGI's affiliates focusing on large scale production of transgenic and cloned animals. "Peng Peng is developing normally and appears healthy" she added.

The project has been launched more than two years ago. Apart from the general inefficiency of cloning (only a small fraction of the reconstructed embryos develop to healthy offspring) cloners had to overcome additional difficulties including the special climate and compromised laboratory environment with very basic instruments.

Accordingly, an innovative simplified technique called Handmade Cloning (HMC) was used, with less demand for sophisticated equipment, simplified procedures, lower costs and higher production efficiency.

In 2009, donor cells were collected from a Chinese Merino sheep, and by genetic manipulation a transgenic cell line was established. After numerous attempts, the HMC system for sheep cloning was successfully established in October 2011. The transfer of the produced embryos has eventually led to the present achievement.

The genetic modification may result in improved meat quality by increasing the unsaturated fatty acid content. According to the researchers, the gene associated with?-3 poly unsaturated fatty acid (?-3PUFA) was successfully transferred into Peng Peng. ?-3PUFAs serve as essential fatty acids for humans reducing the risk of coronary heart disease and supporting the normal development of the brain, eye and neurons.

"The birth of Peng Peng means that people could absorb ?-3PUFAs by drinking milk or eating meat in the future." said Dr. Du, "The most difficult task has been accomplished, the transgenic sheep production platform is established, we are ready for the industrial-scale development."

Since HMC was introduced in 2001, offspring of several important species including cattle, pig, goat and water buffalo have been produced by using this technique. The procedure may contribute to efforts to save endangered species and to produce medicines for human diseases through transgenic animals.

Last year, BGI has made great achievements on cloned transgenic mini-pigs and micro-pigs. Last August, a heroic pig, named Zhu Jiangqiang (Strong-Willed Pig), who had survived more than a month buried under rubble after the 2008 earthquake in China's Sichuan province was also cloned, producing 6 piglets identical with the famous animal.

"With each new species cloned, we learn more about the possible contribution of HMC to improve the health of animals and humans." said Dr. Du. "I expect more breakthroughs on transgenic and cloned animal research in the foreseeable future."

Related Links
BGI Ark Biotechnology
BGI Shenzhen
Farming Today - Suppliers and Technology

Get Our Free Newsletters Via Email
Buy Advertising Editorial Enquiries


. Comment on this article via your Facebook, Yahoo, AOL, Hotmail login.

Share this article via these popular social media networks
del.icio.usdel.icio.us DiggDigg RedditReddit GoogleGoogle

Organic farms yield less produce, require more land: study
Paris (AFP) April 24, 2012
Organic farming may yield up to a third less of some crop types, according to a study proposing a hybrid with conventional agriculture as the best way to feed the world without destroying it. Organic farming seeks to limit the use of chemical pesticides and fertilisers, but critics suggest lower crop yields require bigger swaths of land for the same output as conventional farms. This wou ... read more

Google blasts FCC handling of 'Street View' probe

Latest CryoSat result revealed

CarbonSat - On the trail of greenhouse gases

DigitalGlobe Unveils New Details of WorldView-3 Satellite

NASA Tests GPS Monitoring System for Big US Quakes

SSTL delivers payload for first Galileo FOC satellite

GPS could aid in earthquake warnings

Russia to Test Second Glonass-K Satellite in 2013

Palms reveal the significance of climate change for tropical biodiversity

Rousseff pressed to veto Brazil forestry law

Anti-logging activist shot dead in Cambodian forest

Brazil to boost military presence to protect Amazon wealth

Climate change, biofuels mandate would cause corn price spikes

How the Ecological Risks of Extended Bioenergy Production can be Reduced

Optimizing biofuel supply chain is a competitive game

ANA Celebrate First 787 Biofuel Flight

SunWize Completes the Largest Solar Installation for American Samoa Power Authority

Researchers develop a path to liquid solar cells that can be printed onto surfaces

Ambitious Solar Program in India Drives Prices to Impressive Lows

Scientists discover bilayer structure in efficient solar material

British engineering firm creates 1,000 wind farm jobs

Cape Wind picks contractors for wind farm

Reducing cash bite of wind power

GDF SUEZ, VINCI, CDC Infrastructure and AREVA mobilized for offshore wind power

Nine die in China coal mine blast

Buy coal? New analysis shows purchasing fossil fuel deposits best way to fight climate change

At least 15 dead in two China mine floods

Coal India faces government pressure

China pulls T-shirts featuring premier's quotes

China shuts 'rumour' blogs in Internet crackdown

Major US exhibit opens for Chinese artist Wu

China punishes eight ex-officials of rebel village

Memory Foam Mattress Review

Newsletters :: SpaceDaily Express :: SpaceWar Express :: TerraDaily Express :: Energy Daily
XML Feeds :: Space News :: Earth News :: War News :: Solar Energy News


The content herein, unless otherwise known to be public domain, are Copyright 1995-2012 - Space Media Network. AFP, UPI and IANS news wire stories are copyright Agence France-Presse, United Press International and Indo-Asia News Service. ESA Portal Reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. Advertising does not imply endorsement,agreement or approval of any opinions, statements or information provided by Space Media Network on any Web page published or hosted by Space Media Network. Privacy Statement