Scientists at McMaster University, the University of Melbourne and the University of Illinois found bacteria can develop into illness-causing pathogens by rewiring regulatory DNA, the genetic material that controls disease-causing genes in a body. Previously, disease evolution was thought to occur mainly through the addition or deletion of genes.

"Bacterial cells contain about 5,000 different genes, but only a fraction of them are used at any given time," said McMaster University Assistant Professor Brian Coombes, who led the research. "The difference between being able to cause disease, or not cause disease, lies in where, when and what genes in this collection are turned on. We've discovered how bacteria evolve to turn on just the right combination of genes in order to cause disease in a host."

With infectious diseases on the rise, the finding has implications on how new pathogens are identified in the environment, he said.

"This opens up significant new challenges for us as we move forward with this idea of assigning risk to new pathogens," Coombes said. "Because now, we know it's not just gene content -- it is gene content plus regulation of those genes."

Share This Article With Planet Earth

del.icio.us	Digg	Reddit
YahooMyWeb	Google	Facebook

Related Links
Epidemics on Earth - Bird Flu, HIV/AIDS, Ebola

Memory Foam Mattress Review

SPACE MEDIA NETWORK PROMOTIONS Solar Energy Solutions Tempur-Pedic Mattress Comparison ... Newsletters :: SpaceDaily :: SpaceWar :: TerraDaily :: Energy Daily XML Feeds :: Space News :: Earth News :: War News :: Solar Energy News